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4

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T63745	P-gp modulator 3
	P-gp modulator 3 (Compound 37) 是有效的、竞争性的、变构性 P-glycoprotein (P-gp) 调节剂。
T35531	FD223
	FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML[1].
T83849	OP-145 TFA acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac
	OP-145是一种合成抗菌肽及抗菌肽LL-37的衍生物。它对E. coli、P. aeruginosa、C. albicans和A. niger具有活性（MICs分别为2、3、6和18 µM）。含有OP-145的聚乳酸-共-聚乙二醇酸（PLGA）微球能够在骨折部位接种细菌后通过外科股骨骨折所诱导的小鼠骨感染模型中防止生物膜的形成。
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.2β-Defensin-2 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes.3It also stimulates calcium mobilization, migration, and proliferation of keratinocytes whe...

化合物

P-gp modulator 3

Cat.No: T63745

Cat.No: T35531

Cat.No: T83849

Synonym: acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac

β-Defensin-2 (human) (trifluoroacetate salt)

Cat.No: T35451

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04925	CD8 beta Protein, Human, Recombinant, Biotinylated LY3,LYT3,CD8b molecule,P37,LEU2,CD8 β,CD8B...	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-02703	CD8 beta Protein, Human, Recombinant (hFc) LYT3,CD8 β,CD8b molecule,LY3,P37,LEU2,CD8B...	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is P10966-1.
TMPY-02925	CD8 beta Protein, Human, Recombinant LEU2,P37,CD8b molecule,LYT3,CD8B1,CD8 β,LY...	Human	HEK293 Cells
	CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-03283	HBP1 Protein, Human, Recombinant (GST) HMG-box transcription factor 1	Human	E. coli
	HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichostatin A (TSA), an inhibitor of HDAC (histone deacetylase), induces p16(INK4A) expression in an HBP1-dependent manner. HBP1 activates or represses the expression of some specific genes during cell growth and differentiation. HBP1 was acetylated by p3/CBP in two regions: repression...

重组蛋白

CD8 beta Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-04925

Species: Human

Expression System: HEK293 Cells

CD8 beta Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02703

Species: Human

Expression System: HEK293 Cells

CD8 beta Protein, Human, Recombinant

Cat.No: TMPY-02925

Species: Human

Expression System: HEK293 Cells

HBP1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-03283

Species: Human

Expression System: E. coli

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